cytome is an open-source single-file multi-omics data format for single-cell biology. It supports single-cell genomics workflows, including scRNA-seq and scATAC-seq data, with SQLite storage and streaming access.
In the Databases (SQL, NoSQL, vector, graph) space, cytome takes a focused approach. It focuses on managing and streaming multi-omics single-cell biology data in a portable single-file format. cytome is an open-source project aimed at bioinformatics researchers and computational biologists. cytome is open source under the BSD-3-Clause license. It ships for the command line, and it can be self-hosted.
GeneCell builds and maintains cytome, and it first shipped in 2026. The project is developed in the open on GitHub with 3 commits in the last 90 days. Among its 5 catalogued features are single-file format, multi-omics data, and SQLite storage.
Summary written by a language model from the project’s public pages.
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