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CLIO Agent

github.com·Infrastructure

CLIO Agent — Autonomous AI agent framework for scientific data management. Part of the IOWarp platform.

Open SourceBSD-3-ClauseWebCLISelf-hosted
CCLIO Agent preview
Visit github.com↗
8stars
2forks
8features
2025since

Overview

8 features

In the Autonomous agents & workflows space, CLIO Agent takes a focused approach. It focuses on automating and managing scientific data workflows using autonomous AI agents. It is built as an open-source project for scientific researchers. The project is open source (BSD-3-Clause). It runs on the web and the command line, and it can be self-hosted.

Behind CLIO Agent is IOWarp, and it first shipped in 2025. The project is developed in the open on GitHub with 148 commits in the last 90 days. Key capabilities include agent orchestration, scientific data management, and multi-agent support. It exposes integrations via an MCP server.

  • ✓Agent orchestration
  • ✓Scientific data management
  • ✓Multi-agent support
  • ✓A2A protocol
  • ✓HPC integration
  • ✓Registry support
  • ✓Arc memory
  • ✓Data IO optimization
Tags
ai-agent-frameworkscientific-datamulti-agenthpc-integrationdata-automation
AI capabilities
Structured
Inference: LocalWeights: Open

Built with & integrations

Framework
FastAPI
Connectors
MCP
Runs on
BrowserCLISelf-hosted

Trust & compliance

License
BSD-3-Clause
Verified signals
✓HTTPS✓Open Source✓Free tier✓GitHub · ★ 8✓Active maintenance

Indexing history

1

What PulseGate has recorded for this listing

  1. Indexed16 Jun · 03:07 UTC
    Listing verified against its public source
    Source: PulseGate · Open ↗

Frequently asked questions about CLIO Agent

What is CLIO Agent?
CLIO Agent focuses on automating and managing scientific data workflows using autonomous AI agents. It is catalogued under Autonomous agents & workflows on PulseGate.
Who should use CLIO Agent?
CLIO Agent is an open-source project built for scientific researchers.
Does CLIO Agent have a free plan?
Yes — CLIO Agent is open source under the BSD-3-Clause license and free to use.
What platforms does CLIO Agent run on?
CLIO Agent runs on the web and the command line. It can also be self-hosted.
Is CLIO Agent still maintained?
The GitHub repository shows 148 commits in the last 90 days.
What are alternatives to CLIO Agent?
Similar projects tracked by PulseGate include agent-clifs, CIRIS Ethical AI Agent, and Agent Brain CLI.agent-clifsCIRIS Ethical AI AgentAgent Brain CLI
Who develops CLIO Agent?
CLIO Agent is developed by IOWarp.
When did CLIO Agent launch?
CLIO Agent first shipped in 2025.

At a glance

Platforms
Cli
Languages
English
Open source
Yes · ★ 8
License
BSD-3-Clause
Built for
scientific researchers
Model
Open source
Solves
Automating and managing scientific data workflows using autonomous AI agents.

Registered as

GitHub
iowarp/clio-agent
PyPI
clio-agent

Developer

IOWarp
Small team
↗ GitHub

Open source

View on GitHub →
Stars
8
Forks
2
Open issues
36
Last commit
16 Jun 2026
Commits 90d
148
Contributors
4
Authorship
Small team
Default branch
main
Latest release
v0.3.1 · 27 Apr 2026

Index record

Identity confidence
Medium · 77.4
Indexed
16 Jun 2026
Lifecycle
Alive
Last seen
16 Jun 2026
Identity audit (12)
Slug
clio-agent-pypi-org
Lifecycle last checked
8 Aug 2026
Verification state
Indexed for public listing
Listing state
Listed: yes
Index status
Included in index
Latest evidence snapshot
16 Jun 2026
Timeline basis
Indexed-at chronology. This listing's first-seen date was written by the catalog backfill, not observed here, so it is not treated as a sighting.
Name from
Written by a language model from the project's public pages.
Category from
Assigned by the 2026 taxonomy migration.
Summary from
Taken from the package registry entry.
Languages from
Detected by a language model from page content.
Canonical URL
https://github.com/iowarp/clio-agent

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  • ABAgent Brain CLIgithub.com
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  • PLplayagentgithub.com