gffbase is an open-source, Rust-accelerated parser for GFF3/GTF genomic annotation files with DuckDB-backed storage and a Python API. It streamlines bioinformatics data processing for researchers and developers.
gffbase sits in PulseGate's Other dev tools category. It focuses on accelerating and simplifying the parsing and storage of genomic annotation files for bioinformatics workflows. It is built as an open-source project for bioinformaticians. gffbase is open source under the Apache-2.0 license. gffbase is available on the command line.
gffbase first shipped in 2026. Development happens publicly on GitHub with 29 commits in the last 90 days. Key capabilities include GFF3/GTF parsing, duckDB storage, and rust acceleration.
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