cis-gs is an open-source bioinformatics tool for whole-genome cis-element discovery, expression coupling, and KEGG enrichment analysis. It provides both a PyQt5 GUI and CLI pipeline, supporting genomics researchers in regulatory element analysis.
In the Other dev tools space, cis-gs takes a focused approach. It focuses on automating genome-wide discovery and analysis of cis-regulatory elements for bioinformatics research. It is built as an open-source project for bioinformatics researchers and genomics scientists. cis-gs is open source under the MIT license. cis-gs is available on the command line, Windows, macOS, and Linux, and it can be self-hosted.
It is developed by Ayushmania2002 (GitHub), and the product first shipped in 2025. Development happens publicly on GitHub with 38 commits in the last 90 days. PulseGate's similarity index finds few close equivalents — cis-gs occupies a relatively distinct niche. Key capabilities include genome scanning, cis-element discovery, and KEGG enrichment.
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